What is the CAS number for SB 431542?

The CAS number of SB 431542 is 301836-41-9.

What is SB 431542 (301836-41-9) used for?

SB-431542 is a potent and selective inhibitor of the TGF-ß1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. SB-431542 specifically blocks Smad signaling, reducing gene expression relevant to fibrosis and cancer. Through its effects on ALK/Smad signaling, SB-431542 suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation.InChI:InChI=1/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)

What is the CAS number for SB 431542?

The CAS number of SB 431542 is 301836-41-9.

What is SB 431542 (301836-41-9) used for?

SB-431542 is a potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. SB-431542 specifically blocks Smad signaling, reducing gene expression relevant to fibrosis and cancer. Through its effects on ALK/Smad signaling, SB-431542 suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation.InChI:InChI=1/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)

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SB 431542

CasNo：301836-41-9
purity：99%

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Quality Manufacturer Supply High Purity 99% SB 431542 301836-41-9 with Reasonable Price We supply high quality SB 431542 (CAS 301836-41-9), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the SB 431542 ?

SB 431542 is , while it's Molecular Formula is C22H16N4O3. SB 431542 is a known Src family kinase inhibitor that effectively blocks the transforming growth factor-β1-induced cell migration and invasion in both established and primary carcinoma cells. Potent TGF-beta inhibitor.

How to get the best price on SB 431542?

TIANJIN BAOLIRUITE CHEMICALS CO.,LTD is a quality supplier and manufacturer of SB 431542 . You can buy high quality, low price SB 431542 301836-41-9 here. Contact us.

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